Relevant Selected Publications Providing the Scientific Basis for RhinoCytes tm Technology

Roisen F.J., Klueber K.M., Shields C.B., Lu C.L., Hatcher L.M., Maguire S. (2001) Adult human olfactory stem cells.  Brain Research. 890: 11-22.

Othman M., Klueber K.M., Roisen F.J. (2003) Identification and culture of olfactory neural progenitors from GFP mice. Biotechnic & Histochemistry. 78(2):57-70.

Zhang X., Klueber K.M., Guo Z., Lu C., Roisen F.J. (2004) Adult Human Olfactory Neural Progenitors Cultured in Defined Medium. Experimental Neurology, 186(2):112-123.

Winstead W., Marshall CT, Lu CL, Klueber KM, Roisen F.J. (2005) Endoscopic Biopsy of Human Olfactory Epithelium as a Source of Neural Stem Cells. American Journal of Rhinology. 19(1):83-90.

Zhang X., Cai J., Klueber K.M., Guo Z., Lu C., Qiu M., Roisen F.J. (2005) Induction of oligodendrocytes from adult human olfactory epithelial-derived progenitors by lineage transcription factors. Stem Cells. 23:442-453.

Xiao M., Klueber K.M., Lu C., Guo Z., Wang H., Roisen F.J. (2005) Human adult olfactory neural progenitors rescue axotomized rodent rubrospinal neurons and promote functional recovery. Experimental Neurology. 194:12-30.

Marshall C.T., Guo Z., Lu C., Klueber K.M., Khalyfa A., Cooper N.G.F., Roisen F.J. (2005) Human adult olfactory neuroepithelial derived progenitors retain telomerase activity and lack apoptotic activity. Brain Research. 1045:45-56.

Othman, M., Klueber K., Lu C., Winstead W., Roisen F.J.  (2005a)  Immunomagnetic separation of adult human olfactory neural progenitors.  Biotechnic & Histochemistry, .80, 5-6:177-188.

Othman M., Lu C., Klueber K., Winstead W., Roisen F.J.  (2005b) Clonal analysis of adult human olfactory neurosphere forming cells.  Biotechnic & Histochemistry, 80, 5-6:189-200.

Zhang X., Cai J., Klueber K.M., Guo Z., Lu C., Winstead W.I., Qiu M., Roisen F.J.  (2006) Role of Transcription Factors in the Motoneuron Differentiation of Adult Human Olfactory Neuroepithelial-Derived Progenitors.  Stem Cells, 24: 434-442.

Zhang X., Klueber K.M., Guo Z., Cai J., Lu C., Winstead W.I., Qiu M., Roisen F.J.  (2006)  Induction of neuronal differentiation of adult human olfactory neuroepithelial-derived progenitors.   Brain Research, 1073-1074:109-119.

Marshall C.T., Lu C., Winstead W., Zhang X, Xiao M., Harding G., Klueber K.M., Roisen F.J.  (2006)  The Therapeutic   Potential of Human Olfactory-Derived Stem Cells.  Histology and Histopathology, 21(6):633-643.

Khalyfa A., Buassa M., Qiang H., Xu M., Marshall C.T., Roisen F.J., Kluber K.M., Cooper N.G.F. (2007) Gene expression profiling for adult human olfactory
neuroepithelial-derived progenitors. Gene Therapy Molecular Biology, 11:203-216.